A nurse is providing teaching to a client who has a new prescription for transdermal nitroglycerin patches to treat angina pectoris.Which of the following instructions should the nurse include in the teaching?

Choice A rationaleRemoving the patch for two to four hours daily helps prevent tolerance development by allowing nitrate-free intervals, thus maintaining the effectiveness of nitroglycerin.Choice B rationaleApplying a new patch each day after waking up ensures continuous delivery of nitroglycerin; however, this does not provide nitrate-free intervals necessary to avoid tolerance.Choice C rationaleCovering the patch with plastic wrap can increase the risk of overdose by enhancing nitroglycerin absorption, which may lead to severe hypotension and other adverse effects.Choice D rationaleReplacing the patch as soon as anginal pain begins does not allow for a consistent delivery system and may lead to erratic blood levels of nitroglycerin, reducing its effectiveness.