A nurse is reinforcing teaching to the guardians of a 4-year-old child about the expected reactions of immunizations. Which of the following statements should the nurse include?

Immunizations stimulate the immune system to develop protection against specific infectious diseases. After vaccination, mild and short-term reactions are common as the body mounts an immune response. These expected effects are generally self-limiting and indicate normal immune activation rather than complications. Guardians should be taught which reactions are normal and which require medical attention to ensure safe post-vaccination care. Rationale: A. Developing hives is not an expected reaction and may indicate a hypersensitivity or allergic reaction to the vaccine or its components. Hives are suggestive of an immune-mediated response that requires prompt medical evaluation rather than routine post-immunization care. B. Hyperactivity is not a recognized reaction to immunizations. Behavioral changes such as hyperactivity are not associated with vaccine administration. Expected responses are typically localized discomfort or mild systemic symptoms, not significant behavioral alterations. C. Tenderness at the injection site is an expected and common local reaction following immunization. This occurs due to localized inflammation as the immune system responds to the vaccine. Mild pain, redness, or swelling at the injection site is normal and typically resolves within a few days without intervention. D. A temperature over 102.2°F is not considered a typical or expected response to routine immunizations. Although a low-grade fever may occur, high fever suggests a more significant reaction or possible infection that requires medical evaluation. Guardians should be advised to report high or persistent fevers to the healthcare provider.