A nurse is reinforcing teaching with a client about naltrexone. Which of the following statements by the client indicates an understanding of the teaching?
Explanation & Rationale
Introduction: Naltrexone is an opioid antagonist used in the treatment of alcohol and opioid use disorders. It works by blocking the mu-opioid receptors, thereby interfering with the dopaminergic reward system and reducing the pleasurable effects associated with substance consumption, which helps diminish the urge to drink. A. This statement describes a disulfiram-like reaction. Naltrexone does not cause severe respiratory distress or the "aldehyde syndrome" (nausea, vomiting, palpitations) when alcohol is ingested. Disulfiram is the medication that causes a toxic physical reaction to discourage alcohol consumption through aversive conditioning, not naltrexone. B. Naltrexone does not treat or prevent the physiological symptoms of acute alcohol withdrawal, such as tremors, seizures, or delirium tremens. Clients must undergo detoxification before starting naltrexone, as its primary role is maintenance and relapse prevention by reducing the psychological drive to consume alcohol after withdrawal. C. The goal of naltrexone therapy is usually abstinence rather than a gradual reduction in intake, although some protocols exist. However, the drug itself does not "allow" a decrease; it facilitates the process by altering the brain's reward response. The statement lacks the scientific accuracy of how the drug functions. D. This statement correctly identifies the primary therapeutic effect of naltrexone. By antagonizing the reward pathways in the brain, the medication significantly lowers the intensity of cravings. This pharmacological action makes it easier for the client to maintain sobriety by reducing the obsessive thoughts about consuming alcohol.