A nurse is reinforcing teaching with a client who has a new prescription for enoxaparin. The nurse should identify which of the following over-the- counter products as unsafe for use with enoxaparin?

A. Cimetidine: Cimetidine is an H2-receptor antagonist used for gastric acid reduction. It does not significantly increase the risk of bleeding when taken with enoxaparin and is generally considered safe for concurrent use. B. Docusate: Docusate is a stool softener and does not affect coagulation. It is safe to use with enoxaparin and can help prevent constipation associated with reduced mobility or opioid use. C. Calcium supplement: Calcium supplements do not impact anticoagulation or platelet function. They are safe to take with enoxaparin and do not increase bleeding risk. D. Naproxen: Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits platelet function and can increase the risk of bleeding when taken with enoxaparin. Clients should avoid NSAIDs unless approved by the provider and use alternative pain management strategies.