A nurse is reinforcing teaching with a client who has a new prescription for nitroglycerin transdermal patches to treat angina. The nurse should inform the client that which of the following manifestations is an adverse effect of the medication?

B. Headache, particularly a pounding headache or throbbing sensation, is a well-known side effect of nitroglycerin use. It occurs due to the vasodilatory effects of nitroglycerin, which can lead to dilation of blood vessels in the head and neck. A. Ringing in the ears, also known as tinnitus, is not a common adverse effect of nitroglycerin. Tinnitus is typically associated with certain medications, exposure to loud noises, or underlying medical conditions such as inner ear disorders. It is not a recognized adverse effect of nitroglycerin. C. Nitroglycerin is not known to increase blood pressure. In fact, it typically causes vasodilation and can lead to a decrease in blood pressure, especially when used sublingually or transdermally. Hypotension, rather than hypertension, is a potential adverse effect of nitroglycerin therapy. D. Polyuria, or excessive urination, is not a recognized adverse effect of nitroglycerin. Polyuria may occur as a result of other medications or underlying medical conditions affecting renal function, but it is not directly associated with nitroglycerin use.