A nurse is reinforcing teaching with a client who has a new prescription for nitroglycerin transdermal patches to treat angina. The nurse should inform the client that which of the following manifestations is an adverse effect of the medication?

A. Headache: Headaches are a common adverse effect of nitroglycerin due to vasodilation and increased blood flow to the brain. B. Polyuria: Nitroglycerin does not affect urinary output. C. Ringing in the ears: Tinnitus is not associated with nitroglycerin use. D. Increased blood pressure: Nitroglycerin causes vasodilation, which typically lowers blood pressure rather than increasing it.