A nurse is reinforcing teaching with a client who has a prescription for lithium. Which of the following instructions should the nurse include? (Select all that apply.)

A. "You should take lithium with meals.": Taking lithium with food helps reduce gastrointestinal upset, such as nausea or abdominal discomfort, which is a common side effect. This instruction supports adherence and client comfort while on therapy. B. "You should limit your fluid intake to four 8-ounce glasses daily.": Lithium therapy requires maintaining adequate hydration, as dehydration increases the risk of lithium toxicity. Limiting fluids is unsafe and can precipitate adverse effects. C. "You should not take diuretics while taking this medication.": Diuretics can alter sodium and fluid balance, which may increase lithium levels and the risk of toxicity. Clients should avoid diuretics unless prescribed and monitored by the healthcare provider. D. "You should expect to have lithium blood level testing frequently.": Frequent monitoring of serum lithium levels ensures therapeutic dosing while preventing toxicity, especially during dose adjustments or changes in hydration or renal function. E. "You should drink orange juice to enhance the absorption of this medication.": Citrus juices do not enhance lithium absorption, and this instruction is not supported. Lithium absorption is not significantly affected by specific beverages.