A nurse is reinforcing teaching with a client who has benign prostatic hypertrophy and has a new prescription for finasteride. Which of the following information should the nurse include in the teaching?

A. Decreased libido is an adverse effect of the medication: Finasteride can reduce dihydrotestosterone levels, which may lead to sexual side effects such as decreased libido, erectile dysfunction, or decreased ejaculate volume. Clients should be informed about these potential effects so they can monitor and report any concerns. B. Prostate-specific antigen (PSA) levels will increase while taking this medication: Finasteride actually lowers PSA levels by about 50% over time, which can affect prostate cancer screening. Clients should be aware that PSA results may be artificially reduced and should be interpreted accordingly. C. Expect to experience a response from the medication in 1 week: Finasteride works slowly, and clinical improvement in urinary symptoms usually takes several months, often around 3 to 6 months. Expecting rapid relief within one week is unrealistic. D. Avoid taking the medication with grapefruit juice: There is no significant interaction between finasteride and grapefruit juice. Dietary restrictions of this type are unnecessary, so clients do not need to avoid grapefruit while taking the medication.