A nurse is reinforcing teaching with a client who is pregnant and has a prescription for Rho(D) immune globulin. Which of the following information should the nurse include?

Choice A rationale Rho(D) immune globulin, also known as RhoGAM, is an immunoglobulin product administered to Rh-negative individuals to prevent isoimmunization. It works by binding to and neutralizing any fetal Rh-positive red blood cells that may enter the maternal circulation, thereby preventing the maternal immune system from recognizing these cells and forming anti-Rh antibodies. Choice B rationale This statement is incorrect. Rho(D) immune globulin does not destroy pre-formed Rh antibodies in a woman. Its mechanism of action is prophylactic, preventing the initial sensitization and antibody formation, rather than treating existing antibodies. Once antibodies are formed, RhoGAM is ineffective. Choice C rationale This statement is incorrect. Rho(D) immune globulin is administered to the Rh-negative mother, not the Rh-positive newborn. The purpose is to protect future Rh-positive fetuses from maternal Rh antibody attack, as maternal antibodies can cross the placenta and cause hemolytic disease of the newborn. Choice D rationale This statement is incorrect. Rho(D) immune globulin is administered to the Rh-negative mother to prevent her immune system from forming antibodies. It does not directly act on the newborn or prevent antibody formation within the newborn. The focus is on maternal sensitization.