A nurse is reinforcing teaching with a client who is taking oral prednisone for long-term management of chronic asthma. Which of the following information should the nurse include in the teaching?

A. Rinsing the mouth out after each dose is necessary for inhaled corticosteroids, not oral ones, to prevent oral thrush and other infections. B. Prednisone is typically taken with food to minimize gastrointestinal irritation. C. Prednisone is a corticosteroid that can cause bone loss and osteoporosis when used for long-term management of chronic asthma. Therefore, the client should take a calcium supplement to prevent or reduce the risk of these complications. D. Weight gain, rather than weight loss, is a common side effect of prednisone use. Informing the client about potential changes in weight is important, but the expected effect is usually weight gain.