A nurse is reinforcing teaching with an adolescent about self-administration of insulin. Which of the following instructions should the nurse include?

A. "You should administer your insulin into a muscle.": Insulin is meant for subcutaneous injection, not intramuscular. IM injection can alter the absorption rate, increasing the risk of hypoglycemia or poor glycemic control. B. "You should administer your medication at a 45-degree angle.": A 45-degree angle may be appropriate in very thin individuals, but most adolescents have enough subcutaneous tissue for a 90-degree injection using a short needle. C. "You should chill your medication before administration.": Insulin should be kept refrigerated until use, but it should be brought to room temperature before injection to reduce injection site discomfort. It should not be chilled immediately before use. D. "You should rotate sites when administering the medication.": Rotating injection sites helps prevent lipodystrophy and promotes consistent insulin absorption. Common sites include the abdomen, thigh, upper arm, and buttocks.