A nurse is reinforcing teaching with an adolescent who has a prescription for tretinoin topical for the treatment of acne. Which of the following instructions should the nurse include in the teaching?

A. Tretinoin should be applied at night, not in the morning, as it can increase sensitivity to sunlight and may cause sunburn. B. It is recommended to use a small, pea-sized amount of tretinoin, not a dime-sized amount, to avoid overuse and irritation. C. Tretinoin makes the skin more sensitive to the sun, so it is important to use sunscreen with an SPF of 15 or higher to protect the skin from sun damage while using the medication. D. After washing the face, it is recommended to wait 20-30 minutes before applying tretinoin, not just 5 minutes, to allow the skin to dry and reduce irritation.