A nurse is reinforcing teaching with an adolescent who has a prescription for tretinoin topical for the treatment of acne. Which of the following instructions should the nurse include in the teaching?

A. Using a dime-sized amount of the medication is not the recommended instruction for tretinoin. A small, pea-sized amount is typically advised to avoid irritation and overuse. B. Tretinoin should be applied at night, not in the morning, as it increases sensitivity to sunlight and can cause irritation when exposed to sunlight. C. It is generally recommended to wait 20-30 minutes after washing the face before applying tretinoin, not just 5 minutes. This allows the skin to dry completely, reducing irritation. D. Tretinoin can cause skin sensitivity, making the skin more prone to sunburn. Using a sunscreen with SPF 15 or higher is crucial to protect the skin from harmful UV rays while using tretinoin.