A nurse is reviewing agency protocol prior to administering epoetin alfa to a client who has chronic kidney disease. Which of the following actions should the nurse plan to take?
Explanation & Rationale
A. Shake the vial of medication to dissolve particulates: Epoetin alfa should not be shaken, as shaking can cause denaturation of the protein and result in ineffective medication. The vial should be gently swirled if needed, but not shaken. B. Thaw the medication in the vial 30 min before administration: Epoetin alfa should be stored in the refrigerator and can be allowed to reach room temperature before administration. However, it should not be thawed by direct heat or excessive time, as this could alter its efficacy. C. Discard the vial of medication if the solution is cloudy: Epoetin alfa should not be used if the solution appears cloudy or contains particles, as this could indicate contamination or degradation of the medication. The vial should be discarded in such cases. D. Dilute the vial of medication with sterile water: Epoetin alfa should not be diluted with sterile water or any other solution. It is administered as a single-dose vial, and dilution is not necessary or recommended.