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    ATI Pharmacology Proctored Exam 1 II

    A nurse is reviewing the health history of a client who experiences migraine headaches and has asked about a prescription for sumatriptan.Which of the following conditions should the nurse identify as a contraindication for taking sumatriptan?

    Explanation & Rationale

    Choice A rationaleAsthma is a respiratory condition affecting airways, not directly related to sumatriptan contraindications. Sumatriptan's primary concern is vascular effects, not respiratory involvement. Normal peak expiratory flow rates: 400-600 L/min.Choice B rationaleKidney disease impairs excretion and drug metabolism, but sumatriptan metabolism mainly occurs in the liver, not kidneys. Normal serum creatinine: 0.5-1.2 mg/dL.Choice C rationaleRheumatoid arthritis affects joints and immune response. Sumatriptan contraindications focus on vascular effects, unrelated to rheumatoid arthritis. Normal rheumatoid factor: less than 15 IU/mL.Choice D rationaleCoronary artery disease involves narrowed blood vessels, increasing risk of vasospasm from sumatriptan. Normal blood pressure: 120/80 mmHg. Contraindications: ischemic heart disease, stroke history.

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