A nurse is reviewing the health history of a client who has osteoporosis. Which of the following medications in the client's history contributes to osteoporosis?

A. Long-term glucocorticoid therapy accelerates bone resorption, decreases bone formation, and reduces calcium absorption, all of which contribute to osteoporosis. B. NSAIDs are not associated with bone loss; they are more commonly used for pain and inflammation management. C. Oral antidiabetic medications primarily affect blood glucose regulation, not bone density. D. Cardiac glycosides (e.g., digoxin) affect heart function but are not linked to osteoporosis development.