A nurse is reviewing the laboratory findings for a female client who is taking zidovudine to treat HIV. Which of the following should the nurse identify as an adverse finding associated with this medication?

A. "Neutrophil count 650/mm3 (2,500 to 8,000/mm3)": Zidovudine can cause bone marrow suppression, which can lead to neutropenia (low neutrophil count). A neutrophil count of 650/mm3 is significantly below the normal range and indicates an increased risk for infection. This is a known adverse effect of zidovudine. B. "Platelets 450,000/mm3 (150,000 to 400,000/mm3)": This platelet count is slightly elevated but not typically a concern related to zidovudine use. Thrombocytopenia is more commonly associated with zidovudine, rather than an elevated platelet count. C. "Hgb 17 g/dL (12 to 16 g/dL)": This hemoglobin level is slightly elevated but not significantly concerning in the context of zidovudine use. Zidovudine can cause anemia, but this hemoglobin level is above the normal range for females. D. "Creatinine 1.5 mg/dL (0.5 to 1 mg/dL)": An elevated creatinine level can indicate kidney dysfunction, but it is not a common adverse effect of zidovudine. Zidovudine primarily affects bone marrow, not kidney function, though renal impairment should still be monitored.