A nurse is reviewing the medical history of a client who is to start taking prednisone. Which of the following findings should the nurse identify as a contraindication to prednisone therapy?

B. Prednisone can suppress the immune system, making it difficult to fight fungal infections. Using prednisone in the presence of untreated systemic fungal infections can worsen the infection and lead to systemic spread.A. While prednisone does not have an absolute contraindication for individuals with a prior history of kidney stones, caution is warranted. Monitoring for signs of kidney stone formation and ensuring adequate hydration may be necessary.C. Prednisone is often prescribed for its anti-inflammatory effects, which can help reduce airway inflammation during asthma exacerbations.D. There is no direct contraindication between prednisone and levothyroxine. However, prednisone can interfere with thyroid function tests by altering thyroid hormone metabolism.