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    Ati Pn Pharmacology 2023 Proctored Exam

    A nurse is reviewing the medical record of a client who has a new prescription for celecoxib to treat osteoarthritis. Which of the following should the nurse recognize as a contraindication for this medication?

    Explanation & Rationale

    A. Celecoxib is contraindicated in individuals with a history of hypersensitivity reactions, including anaphylaxis, angioedema, or urticaria, to sulfonamides. Sulfonamide antibiotics are structurally related to sulfonamide nonantibiotics, including celecoxib, and cross-sensitivity reactions may occur in some individuals. B. Penicillin allergy is not a contraindication for celecoxib. There is no cross-reactivity between penicillin antibiotics and celecoxib, as they are different classes of medications. C. Concurrent use of chondroitin is not a contraindication for celecoxib. Chondroitin is a dietary supplement commonly used for joint health, and there are no known interactions or contraindications between chondroitin and celecoxib. D. Concurrent use of calcium supplements is not a contraindication for celecoxib. There are no known interactions between calcium supplements and celecoxib, and they can be safely used together if indicated.

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