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    RN Comprehensive Predictor 2023 Proctored Exam

    A nurse is reviewing the medical record of a male client who has schizophrenia and is taking clozapine. Which of the following findings should the nurse identify as a contraindication to the administration of clozapine?

    Explanation & Rationale

    A. Hemoglobin of 12.5 g/dL is slightly low but not a contraindication for clozapine therapy. B. Clozapine can cause agranulocytosis, a severe drop in neutrophils, increasing the risk of infection. A neutrophil count below 1,500/mm³ is a contraindication, requiring immediate discontinuation. C. A heart rate of 58/min is not a concern unless symptomatic bradycardia is present. D. A fasting blood glucose of 124 mg/dL is slightly elevated, but clozapine can cause metabolic changes, so this is expected and should be monitored, not discontinued.

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