ATI RN Comprehensive Predictor 2023 Updated Proctored Exam
A nurse is reviewing the medical record of a male client who has schizophrenia and is taking clozapine. Which of the following findings should the nurse identify as a contraindication to the administration of clozapine?
Explanation & Rationale
A. Elevated fasting blood glucose is a concern but does not immediately contraindicate clozapine administration. It can be monitored and managed. B. Clozapine can cause agranulocytosis, and a low absolute neutrophil count (ANC) is a contraindication for the medication. The threshold for stopping clozapine is typically an ANC of less than 1,500/mm3. C. A heart rate of 58/min is not a contraindication for clozapine. It may require monitoring but is not necessarily concerning. D. An Hgb level of 12.5 g/dL is within the normal range and does not contraindicate the use of clozapine.
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