A nurse is reviewing the medication administration record of a client who has benign prostatic hyperplasia (EPH). The client asks the nurse about taking saw palmetto. The nurse should instruct the client that which of the following medications interacts adversely with saw palmetto?

A. Zolpidem (a sedative-hypnotic) has no known major interaction with saw palmetto. B. Ipratropium is an inhaled bronchodilator with no interaction with herbal supplements like saw palmetto. C. Saw palmetto, used for relieving urinary symptoms of BPH, has antiplatelet properties that can increase the risk of bleeding when taken with anticoagulants or antiplatelet drugs such as clopidogrel, warfarin, or aspirin. The nurse should caution the client about concurrent use and notify the healthcare provider. D. Penicillin is an antibiotic and does not interact with saw palmetto.