A nurse is reviewing the medication administration record of a client who has rheumatoid arthritis and is 1 day postoperative following a left total hip arthroplasty. Which of the following medications places the client at risk for delayed wound healing?

Rationale: A. Omeprazole: Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and prevent gastrointestinal irritation, especially in clients taking NSAIDs. It does not interfere with tissue regeneration, collagen formation, or immune responses involved in wound healing. It does not raise concern for impaired postoperative recovery. B. Prednisone: Prednisone is a corticosteroid that suppresses inflammation and decreases immune system activity, which can impair the normal healing process. It slows collagen synthesis, reduces fibroblast activity, and decreases the inflammatory response needed for effective tissue repair. Clients taking prednisone are at increased risk for delayed wound healing. C. Digesin: Digesin is an enzyme-based digestive aid used to support gastrointestinal function and has no impact on tissue repair or immune function. It does not influence collagen production, vascularization, or cellular regeneration. Therefore, it does not contribute to postoperative wound healing complications. D. Morphine: Morphine is an opioid analgesic used for postoperative pain management and does not interfere with the physiologic processes involved in wound healing. Adequate pain control may actually improve recovery by reducing stress responses, enhancing mobility, and promoting better respiratory effort. It does not delay wound tissue repair.