A nurse is reviewing the medication list of a client who has erectile dysfunction and is requesting a prescription for sildenafil. The nurse should identify that which of the following medications is a contraindication for receiving this medication?
Explanation & Rationale
A. Nitroglycerin is commonly used to treat angina (chest pain) and works by dilating blood vessels to increase blood flow to the heart. Both sildenafil and nitroglycerin can cause vasodilation, leading to a significant drop in blood pressure. Concomitant use of sildenafil with nitroglycerin or other nitrates is contraindicated due to the risk of severe hypotension (dangerously low blood pressure) and cardiovascular collapse.B. Albuterol is a bronchodilator used to treat asthma and COPD by relaxing the airway muscles. It does not have significant interactions with sildenafil related to blood pressure.C. Furosemide is a loop diuretic used to treat fluid retention (edema) and hypertension by increasing urine output. Furosemide does not have specific contraindications with sildenafil. While bothmedications can cause a decrease in blood pressure, the concurrent use of furosemide and sildenafil is typically managed by monitoring for signs of hypotension rather than being contraindicated outright.D. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation by inhibiting prostaglandin synthesis. Indomethacin does not have specific contraindications with sildenafil. While NSAIDs can potentially cause renal impairment and fluid retention, leading to increased blood pressure, this is not a direct contraindication for the use of sildenafil.