A nurse is reviewing the medication record of a client who has hypertension. Which of the following medications should the nurse administer to lower the client's blood pressure?

Choice A rationale Promethazine is an antihistamine with sedative and antiemetic properties, primarily used to treat nausea, vomiting, and allergic reactions. It does not exert a significant direct hypotensive effect and is not indicated for the management of hypertension, unlike antihypertensive agents that target blood pressure regulation. Choice B rationale Amlodipine is a dihydropyridine calcium channel blocker widely used to treat hypertension and angina. It works by inhibiting calcium influx into vascular smooth muscle cells, leading to vasodilation, decreased peripheral vascular resistance, and consequently, a reduction in blood pressure, making it an effective antihypertensive agent. Choice C rationale Phenazopyridine is a urinary analgesic that provides symptomatic relief from pain, burning, urgency, and frequency associated with urinary tract infections. It acts locally on the urinary tract mucosa and does not have any systemic effect on blood pressure or a role in the treatment of hypertension. Choice D rationale Fluconazole is an antifungal medication used to treat various fungal infections. Its mechanism of action involves inhibiting fungal cytochrome P450 enzymes necessary for ergosterol synthesis, a vital component of fungal cell membranes. It has no direct pharmacological effect on blood pressure regulation.