A nurse is speaking with a client who called the provider's office to report chest pain and requests clarification about how to take their sublingual nitroglycerin. Which of the following statements should the nurse make?

A. "Wait 5 minutes between doses.": Sublingual nitroglycerin is taken to relieve acute angina episodes. The recommended protocol is to place one tablet under the tongue and, if pain persists, repeat every 5 minutes as needed, up to a maximum of three doses within 15 minutes. Waiting 5 minutes between doses allows the medication to work while monitoring for resolution of symptoms or adverse effects. B. "Place 2 tablets under your tongue.": Only one tablet should be taken initially. Taking multiple tablets at once increases the risk of severe hypotension, headache, and dizziness. Proper dosing is critical to both effectiveness and safety. C. "You can take up to 4 tablets in 20 minutes.": The maximum recommended is three tablets in 15 minutes, not four in 20 minutes. Exceeding this can cause significant hypotension and cardiovascular complications. D. "Drink a full glass of water with the medication.": Sublingual nitroglycerin should not be swallowed or taken with water because it needs to dissolve under the tongue for rapid absorption into the bloodstream. Drinking water would reduce its effectiveness.