A nurse is teaching a client about causes of biliary cirrhosis. Which of the following information should the nurse include in the teaching?

Rationale: A. Hepatotoxic medications can cause toxic or drug-induced liver injury, but they are not the primary cause of biliary cirrhosis. B. Excessive alcohol consumption is a major cause of alcoholic cirrhosis, not biliary cirrhosis. C. Obstruction of the bile duct—whether from gallstones, strictures, or autoimmune disorders—leads to cholestasis. Over time, the retained bile damages liver cells, causing inflammation, fibrosis, and ultimately biliary cirrhosis. D. Hepatitis C primarily causes viral hepatitis-related cirrhosis, not biliary cirrhosis.