A nurse is teaching a client who has a depressive disorder about fluoxetine (Prozac). Which of the following information should the nurse include in the teaching?

Choice A reason: Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is commonly associated with sexual dysfunction, including decreased libido, delayed orgasm, or erectile difficulties. This is an important teaching point because it can affect adherence to therapy if the client is not prepared for this side effect. Choice B reason: Drooling is not a typical side effect of fluoxetine. Excessive salivation is more commonly seen with antipsychotics such as clozapine, not SSRIs. Choice C reason: Improvement in depressive symptoms with fluoxetine usually takes 2 to 4 weeks, not 2 to 3 days. Clients should be counseled to continue taking the medication consistently and not expect immediate relief. Choice D reason: Appetite changes can occur with SSRIs, but decreased appetite is not a primary or consistent side effect of fluoxetine. Some clients may experience weight changes, but sexual dysfunction is more characteristic.