A nurse is teaching a client who has a new prescription for a transdermal nitroglycerin patch. Which of the following instructions should the nurse include?

Choice A reason: Applying the patch to the same site daily risks skin irritation and reduced absorption. Rotating sites (e.g., chest, arms) ensures efficacy, making this an incorrect instruction. Choice B reason: Removing the nitroglycerin patch at night provides a nitrate-free period, reducing tolerance and maintaining efficacy. This is standard practice, making it the correct instruction for the client. Choice C reason: Cutting the patch disrupts the controlled-release mechanism, causing unpredictable dosing and risks. Dizziness requires medical evaluation, not patch modification, making this incorrect and unsafe. Choice D reason: Limiting application to the upper arm restricts options. Patches can be applied to hairless areas like the chest or back, making this unnecessarily restrictive and incorrect.