A nurse is teaching a client who has a new prescription for ciprofloxacin to treat an uncomplicated UTI. Which of the following instructions should the nurse include?

A. Expect urine to turn dark orange: This is not a common side effect of ciprofloxacin. Some medications, like rifampin, can cause urine discoloration, but ciprofloxacin does not typically result in dark orange urine. B. Take this medication with an antacid: Ciprofloxacin should not be taken with antacids as they can interfere with its absorption, reducing its effectiveness. It’s important to take ciprofloxacin on an empty stomach, at least 2 hours before or 6 hours after taking antacids. C. Drink 1,000 milliliters of fluid daily: The exact amount of fluid needed varies depending on the individual. The nurse should recommend drinking plenty of fluids, but 1,000 milliliters may not be sufficient for everyone, especially those with higher fluid needs. D. Monitor for tendon pain: Ciprofloxacin is associated with an increased risk of tendonitis and tendon rupture, particularly in older adults and those taking corticosteroids. Clients should be advised to monitor for signs of tendon pain, swelling, or rupture.