A nurse is teaching a client who has osteoporosis and a new prescription for alendronate (Fosamax). Which of the following instructions should the nurse provide?

A. Alendronate should be taken on an empty stomach with a full glass of water, at least 30 minutes before any food or other medications. This ensures better absorption. B. Alendronate should not be taken with antacids, as they can interfere with its absorption. The patient should not lie down immediately after taking it to prevent esophageal irritation. C. This is the correct recommendation. Alendronate should be taken in the morning, on an empty stomach, with a full glass of water. The patient should then remain upright for at least 30 minutes. D. Alendronate tablets should be swallowed whole. Crushing or chewing the tablet may increase the risk of esophageal irritation and reduce its effectiveness.