A nurse is teaching a client who has tuberculosis about infection control with her family at home. Which of the following instructions should the nurse include?

A. "Wear a high-filtration mask at home when family members are nearby.": Clients with TB do not need to wear high-filtration masks at home once effective treatment has begun, as transmission risk decreases rapidly. Home precautions focus more on cough hygiene and ventilation rather than continuous mask use inside the home. B. "Before coughing or sneezing, cover your mouth and nose with a tissue.": Covering the mouth and nose prevents airborne spread of Mycobacterium tuberculosis by limiting droplet dispersion. This, combined with immediate disposal of tissues and hand hygiene, is essential for protecting household members. C. "Return to work after two consecutive sputum cultures are negative.": Clearance for work is based primarily on sputum smears, clinical improvement, and provider guidance, not sputum cultures, which take weeks to result. Waiting for negative cultures is unnecessary for determining when a client is no longer infectious. D. "Make sure family members wear masks whenever they are in the same room as you.": Family members generally do not need to wear masks once the client has started effective treatment for several weeks because infectivity significantly decreases. Emphasis is placed instead on good ventilation, cough etiquette, and adherence to medications.