A nurse is teaching a client who is postpartum and has an order for an injection of Rh, (D) immunoglobulin. Which of the following should be included in the teaching?
Explanation & Rationale
A. It prevents the formation of Rh antibodies in mothers who are Rh negative: Rh(D) immunoglobulin works by preventing the maternal immune system from recognizing and forming antibodies against Rh-positive fetal red blood cells. This is essential to protect future pregnancies from hemolytic disease of the newborn. B. It destroys Rh antibodies in mothers who are Rh negative: Rh(D) immunoglobulin does not destroy antibodies that have already formed. If sensitization has occurred, the immunoglobulin is ineffective. It is strictly a preventive measure, not a treatment for existing antibodies. C. It prevents the formation of Rh antibodies in newborns who are Rh positive: Newborns do not form Rh antibodies in response to their own blood type. The immune response in question occurs in the Rh-negative mother, not in the Rh-positive infant. This statement reflects a misunderstanding of the immunologic mechanism. D. It destroys Rh antibodies in newborns who are Rh positive: Rh(D) immunoglobulin does not act on the newborn’s immune system or antibodies. It functions solely in the maternal circulation to prevent maternal sensitization to fetal Rh-positive cells.