A nurse is teaching a group of nurses about the administration of nitroglycerin. Which of the following routes of administration has the most rapid onset for the client?

A. Topical ointment has a slower onset as it must be absorbed through the skin before it can exert its effects. B. Sublingual nitroglycerin provides rapid relief of angina symptoms because it is absorbed quickly into the bloodstream through the mucous membranes in the mouth, allowing for an immediate effect. C. Transdermal patches release nitroglycerin slowly over time, leading to a delayed onset of action. D. Sustained-release formulations are designed for prolonged effects rather than rapid onset, making them slower to take effect compared to sublingual administration.