A nurse is teaching a group of pregnant clients about health screening during pregnancy. When discussing Alpha-fetoprotein (AFP) testing, which of the following statements should be included in the education?

A. Low levels of AFP are not diagnostic of any condition, but they could indicate a potential issue, requiring further investigation. B. A negative AFP test does not rule out genetic issues, as AFP is just one screening tool. C. High levels of AFP may indicate a neural tube defect or other issues and warrant further testing, such as ultrasound or amniocentesis. D. An elevated AFP level is associated with neural tube defects but does not definitively indicate the presence of one without further testing.