A nurse is teaching a newly licensed nurse about routes of medication administration for preschoolers. Which of the following nursing interventions should the nurse include in the teaching? (Select All that Apply.)

A. Using a medicine cup for oral medication administration: Medicine cups allow accurate measurement of liquid medications and are appropriate for preschool-aged children who can cooperate with oral intake. This method reduces dosing errors and facilitates safe administration. B. Instructing the child to swallow sublingual medication: Sublingual medications are designed to dissolve under the tongue for rapid absorption. Preschoolers may lack the developmental ability to hold the medication properly, making this route unsafe without close supervision. This instruction is not routinely appropriate for this age group. C. Administering rectal medication into the client's anus: Rectal administration is a valid route for preschoolers, especially when oral administration is not possible due to vomiting or refusal. Proper technique ensures absorption and minimizes discomfort. D. Selecting a suitable vein for intravenous medication administration: IV administration requires careful vein selection to ensure effective delivery and reduce complications. Preschoolers often need smaller-gauge catheters, and site choice is critical for safety. E. Educating the client on proper inhalation technique for inhaled medication: Preschoolers can be taught to use inhalers with spacers or masks to optimize medication delivery to the lungs. Education helps improve adherence and therapeutic effect. F. Applying topical or transdermal medication directly to the client's open wound: Applying topical medications directly to an open wound is inappropriate unless specifically prescribed for wound care. Standard transdermal patches are intended for intact skin; misuse can lead to systemic toxicity or local irritation.