A nurse is teaching the parents of a pediatric client who has been diagnosed with systemic juvenile idiopathic arthritis (JIA) about long-term effects. Which of the following statements should the nurse include in their teaching?

A. "JIA can cause joint damage leading to permanent deformities and reduced mobility.": Systemic juvenile idiopathic arthritis involves chronic inflammation that can damage cartilage and bone over time. Without effective management, this can result in joint deformities, limited range of motion, and functional impairment, highlighting the importance of long-term monitoring and therapy. B. "JIA has no long-term developmental effects as long as it is treated with NSAIDs.": NSAIDs help manage pain and inflammation but do not prevent all complications. Children with JIA may still experience growth disturbances, joint damage, or delays in physical development despite treatment. C. "The inflammation of the joints experienced with this type of JIA is mild.": Systemic JIA can involve severe, persistent inflammation affecting multiple joints and sometimes organs. Describing it as mild underestimates disease severity and may give parents false reassurance. D. "Most children do not need any treatment beyond monitoring, and they will grow out of this type of JIA.": Systemic JIA often requires pharmacologic interventions such as NSAIDs, corticosteroids, or disease-modifying antirheumatic drugs. The disease does not spontaneously resolve in most cases, and untreated inflammation can cause permanent damage.