A nurse is working in an adult Inpatient unit caring for patient's with inflammatory bowel disease. The nurse knows the following medications are commonly used for treatment of Chron's or Ulcerative Colitis. Select all that apply.

A. lisdexamfetamine: Lisdexamfetamine is a central nervous system stimulant used primarily to treat attention-deficit/hyperactivity disorder (ADHD) and binge-eating disorder. It has no anti-inflammatory or immunomodulatory effects and is not used in the management of Crohn’s disease or ulcerative colitis. B. mesalamine: Mesalamine is an aminosalicylate that acts locally in the gastrointestinal tract to reduce inflammation. It is commonly used in both Crohn’s disease and ulcerative colitis to induce and maintain remission, particularly for mild to moderate disease activity. C. adalimumab: Adalimumab is a monoclonal antibody that inhibits tumor necrosis factor-alpha (TNF-α), a key pro-inflammatory cytokine involved in inflammatory bowel disease. It is indicated for moderate to severe Crohn’s disease and ulcerative colitis, particularly in clients who do not respond to conventional therapy. D. budesonide: Budesonide is a corticosteroid with high topical anti-inflammatory activity in the GI tract and lower systemic absorption than systemic steroids. It is used to treat mild to moderate flares of Crohn’s disease and sometimes ulcerative colitis, reducing inflammation while minimizing systemic side effects. E. datorvastatin: Datorvastatin is a statin used for hyperlipidemia and cardiovascular risk reduction. It has no role in the management of inflammatory bowel disease and does not affect intestinal inflammation.