A nurse on a medical unit is planning care for an older adult client who takes several medications. Which of the following prescribed medications places the client at risk for orthostatic hypotension? (Select all that apply.)

A. Atorvastatin: Atorvastatin is a statin used to manage cholesterol levels and does not typically cause orthostatic hypotension. Its side effects are more related to muscle pain, liver dysfunction, and digestive issues, but it is not associated with lowering blood pressure. B. Telmisartan: Telmisartan is an angiotensin II receptor blocker (ARB) used to treat high blood pressure. ARBs can cause orthostatic hypotension, especially when first starting the medication or increasing the dose, as they lower blood pressure and can lead to dizziness upon standing. C. Duloxetine: Duloxetine is an antidepressant and selective serotonin-norepinephrine reuptake inhibitor (SSNRI). It can cause orthostatic hypotension. It works by altering neurotransmitters involved in blood pressure regulation, which may result in a drop in blood pressure when standing. D. Furosemide: Furosemide is a loop diuretic commonly used to treat edema and hypertension. It works by removing excess fluid from the body, which can decrease blood volume and lead to a drop in blood pressure, especially when standing. E. Clopidogrel: Clopidogrel is an antiplatelet medication used to prevent blood clots. It does not directly affect blood pressure and is not typically associated with orthostatic hypotension. Its main concern is bleeding risk.