A nurse should have a patient remain in the office for 15 minutes following the administration of which of the following medications? Select all that apply.

A. Allergy shot: Patients should be observed for at least 15 minutes after receiving an allergy shot because of the risk of anaphylactic reactions, which can be life-threatening if not treated promptly. B. B12 shot: Observation after a B12 shot is not typically necessary as it is generally well tolerated and does not carry a high risk of immediate allergic reactions. C. Antibiotics: Some antibiotics, especially when given by injection, can cause allergic reactions, including anaphylaxis. Therefore, it’s prudent to observe the patient for 15 minutes after administration. D. Immunizations: Like allergy shots, immunizations can sometimes cause allergic reactions or anaphylaxis, so patients are often observed for 15 minutes following administration.