A nurse should question administering Loperamide (Immodium) to which of the following clients?

A. A client with acute, non-infectious diarrhea.: Loperamide is safe and effective for treating acute, non-infectious diarrhea by slowing intestinal motility. It allows increased absorption of water and electrolytes, helping to reduce stool frequency and improve consistency. B. A client with traveler’s diarrhea.: Loperamide can be used short-term in traveler’s diarrhea when symptoms are not caused by invasive bacteria. It provides symptomatic relief by decreasing bowel movements while the underlying infection is being treated. C. A client with an E. coli infection.: Loperamide should be avoided in clients with infectious diarrhea caused by organisms such as E. coli, Salmonella, or Shigella. Slowing intestinal motility can trap bacteria and toxins in the gut, worsening the infection and increasing the risk of toxic megacolon. D. A client who has hyperactive bowel sounds.: Hyperactive bowel sounds alone are not a contraindication to loperamide use. They are expected with diarrhea and may actually improve as the medication reduces peristaltic activity and stool frequency.