A nursing student asks the nurse to differentiate the pathology of Alzheimer's disease from that of Parkinson's disease.Which description is correct?
Explanation & Rationale
Choice A rationaleParkinson's disease is characterized by an imbalance of dopamine and acetylcholine, primarily due to the degeneration of dopamine-producing neurons in the substantia nigra. This imbalance results in the characteristic motor symptoms of Parkinson's disease, such as tremors, rigidity, and bradykinesia.Choice B rationaleParkinson's disease involves decreased dopamine production, not increased. The disease is caused by the progressive loss of dopamine-producing neurons in the brain, leading to reduced dopamine levels and an imbalance with acetylcholine.Choice C rationaleAlzheimer's disease is not primarily characterized by a decrease in dopamine. Instead, it involves the degeneration of cholinergic neurons and a deficiency in acetylcholine, which is crucial for memory and cognitive functions.Choice D rationaleAlzheimer's disease is associated with a deficiency of acetylcholine rather than an excess. The disease is also characterized by the presence of neuritic plaques and neurofibrillary tangles in the brain, which contribute to cognitive decline.