A nursing student preparing a presentation on arthritis knows that differences between osteoarthritis (OA) and rheumatoid arthritis (RA) include what? (Select All that Apply.)

A. Initial treatment of both OA and RA is usually nonpharmacological using heat or exercise: Nonpharmacological interventions such as heat therapy, joint protection, and exercise are first-line treatments for both conditions. B. Both OA and RA present with joint stiffness lasting 20–30 minutes after rest: In OA, stiffness typically lasts less than 30 minutes and improves with movement, while in rheumatoid arthritis, stiffness often lasts more than 30 minutes and may persist for hours. C. OA usually impacts distal interphalangeal joints; RA impacts proximal interphalangeal joints: Osteoarthritis commonly affects weight-bearing joints and distal finger joints, while rheumatoid arthritis involves symmetric inflammation of smaller joints such as the proximal interphalangeal and metacarpophalangeal joints. D. OA is a localized process, whereas RA may be systemic: Osteoarthritis primarily affects cartilage and underlying bone in specific joints, while rheumatoid arthritis is an autoimmune condition that can affect multiple organ systems. E. Both OA and RA have an acute onset in older adults: Osteoarthritis develops gradually over time due to cartilage wear, whereas rheumatoid arthritis often begins insidiously with progressive joint inflammation. Neither presents as an acute condition in older adults.