A patient admitted with a small-cell lung carcinoma, is noted to have a significant decrease in urine output accompanied by shortness of breath, edema, and mental status changes. The nurse is aware that this clinical presentation is consistent with which disorder?
Explanation & Rationale
Rationale: A. Diabetes insipidus causes polyuria and excessive thirst due to insufficient antidiuretic hormone (ADH) or renal response to ADH. The patient in this scenario has decreased urine output, which is the opposite of diabetes insipidus. B. SIADH is a paraneoplastic syndrome commonly associated with small-cell lung carcinoma, where there is excessive ADH secretion, leading to water retention, hyponatremia, decreased urine output, edema, mental status changes, and sometimes respiratory symptoms. The patient’s oliguria, edema, and altered mental status are consistent with SIADH. C. Myxedema coma is a severe form of hypothyroidism, presenting with hypothermia, bradycardia, hypotension, hypoventilation, and altered mental status. The patient’s small-cell lung carcinoma and urine retention are not consistent with this diagnosis. D. Adrenal crisis involves hypotension, hyponatremia, hyperkalemia, dehydration, and shock due to adrenal insufficiency. While some electrolyte disturbances and mental status changes overlap, the low urine output with edema points more specifically to SIADH rather than adrenal crisis.