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    ATI Advanced Pharmacology Final Proctored Exam

    A patient exhibits ptosis of both eyes and the provider orders edrophonium (Tensilon). The nurse notes immediate improvement of the ptosis.The nurse understands that this patient most likely has which disorder?

    Explanation & Rationale

    Choice A rationaleMyasthenia gravis is an autoimmune neuromuscular disorder characterized by weakness and fatigue of the skeletal muscles. Improvement of ptosis after administration of edrophonium (Tensilon), a short-acting acetylcholinesterase inhibitor, is a diagnostic indicator of myasthenia gravis.Choice B rationaleCerebral palsy is a group of permanent movement disorders that appear in early childhood. It is primarily caused by abnormal development or damage to the brain and does not exhibit rapid improvement with edrophonium.Choice C rationaleMultiple sclerosis is a chronic illness involving the central nervous system, where the immune system attacks the protective sheath (myelin) that covers nerve fibers. It does not respond to edrophonium as myasthenia gravis does.Choice D rationaleMuscle spasm refers to an involuntary contraction of a muscle that can be sudden and painful. This condition is not typically diagnosed or treated with edrophonium, which is specific for myasthenia gravis. .

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