A patient is admitted to the emergency department in shock. Isoproterenol (Isuprel) is admitted. What would the nurse expect the effect of this drug would be?
Explanation & Rationale
A) Decreased blood pressure: Isoproterenol (Isuprel) is a non-selective beta-adrenergic agonist that primarily stimulates beta-1 and beta-2 receptors. It causes vasodilation through beta-2 stimulation, but its predominant effect is increasing heart rate and cardiac output via beta-1 stimulation. This tends to result in an increase in blood pressure B) Decreased heart rate: Isoproterenol generally leads to an increase in heart rate because of its beta-1 adrenergic activity, which stimulates the heart's pacemaker cells. It is commonly used to treat bradycardia (slow heart rate). C) Increased body temperature: Although isoproterenol can lead to increased heart rate and blood flow, it does not directly cause a significant increase in body temperature. Temperature changes are more commonly seen with drugs affecting metabolism or those that induce fever. D) Increased blood pressure: Isoproterenol stimulates beta-1 receptors in the heart, leading to increased heart rate and cardiac output, which typically results in an increase in blood pressure. However, due to its beta-2 effects, there can be some vasodilation, which may counteract this effect slightly. Despite this, the overall effect of isoproterenol is typically an increase in blood pressure, especially in a shock setting, where improving circulation is critical.