A patient is prescribed the centrally acting muscle relaxant baclofen. Which of the following instructions should the nurse include?

A. "Avoid driving anywhere until you know how the medication affects you": Baclofen is a centrally acting muscle relaxant that can cause drowsiness, dizziness, and impaired coordination. Patients should avoid activities requiring alertness, such as driving, until they understand how the medication affects them. B. "Combine this medication with some codeine to enhance the pain-killing effects": Combining baclofen with other CNS depressants like codeine increases the risk of excessive sedation and respiratory depression. Concurrent use should only occur under direct provider guidance. C. "If the first dose doesn't work after 30 minutes, take a second dose": Baclofen dosing should follow the prescribed schedule. Taking extra doses without guidance can lead to overdose, severe drowsiness, or hypotension. D. "If you get drowsy, drink some coffee to stay awake": Attempting to counteract CNS depression with caffeine does not safely mitigate baclofen’s sedative effects. The priority is to adjust activities and avoid situations that require alertness, not to override drowsiness with stimulants.