A patient is reporting sharp pain along the costovertebral angles. What does this symptom most often indicate?

A. Liver enlargement: Pain from liver enlargement is typically felt in the right upper quadrant, not along the costovertebral angle. B. Spleen enlargement: Splenic pain is usually located in the left upper quadrant, not in the costovertebral area. C. Ovarian infection: Pain from ovarian infection is typically felt in the lower abdomen or pelvis, not the back. D. Kidney inflammation: Pain along the costovertebral angles often indicates kidney inflammation or infection, such as pyelonephritis.