A patient is scheduled to have a central venous access device placed for administration of chemotherapy. When preparing the patient for the catheter insertion, the nurse explains that this method of administration is preferred for which reason?

A. It decreases the risk for extravasation at the infusion site: Central venous access devices (CVADs) are preferred for chemotherapy because they deliver highly vesicant or irritant medications directly into a large central vein. The rapid dilution in high-flow vessels reduces the risk of local tissue damage (extravasation), which can occur with peripheral IV administration. B. It reduces the incidence of systemic side effects of the medication: CVADs do not inherently reduce systemic side effects, as chemotherapy affects both tumor and normal cells systemically. The method of administration mainly affects local tissue safety rather than systemic toxicity. C. It allows continuous infusion of the medication directly to the tumor: Chemotherapy delivered via a central line enters systemic circulation, not directly to the tumor site. Tumor targeting depends on pharmacologic properties, not catheter placement. D. It does not become occluded as peripherally inserted catheters can: While CVADs are designed for long-term use, they can still become occluded due to thrombus formation or medication precipitates. Occlusion is not entirely prevented; proper maintenance and flushing protocols are required to reduce this risk.