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    ATI Nurs 520 Pharmacology proctored Exam

    A patient receives a drug that has a narrow therapeutic range. The nurse administering this medication will expect to do what?

    Explanation & Rationale

    Choice A reason: Drugs with a narrow therapeutic range, like digoxin, require plasma level monitoring to ensure concentrations remain within a safe and effective range. This prevents toxicity (e.g., arrhythmias) or subtherapeutic effects, as small dose changes can significantly alter blood levels, making monitoring critical for patient safety and efficacy. Choice B reason: Intravenous administration does not inherently address the risks of a narrow therapeutic range. While it ensures rapid delivery, it increases toxicity risk due to immediate bioavailability. Monitoring plasma levels is more critical than the route to maintain safe and effective drug concentrations, making this choice less appropriate. Choice C reason: Administering at intervals longer than the half-life may lead to subtherapeutic levels for drugs with a narrow therapeutic range, reducing efficacy. Consistent dosing and plasma level monitoring are needed to maintain steady-state concentrations within the therapeutic window, making this choice incorrect for managing such drugs. Choice D reason: Teaching that maximum effects occur quickly is inaccurate for most narrow therapeutic range drugs, which often require steady-state concentrations over time. Without monitoring, toxicity or inefficacy risks increase. Patient education should focus on adherence and monitoring, not rapid effects, making this choice inappropriate.

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